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However, their dysfunction, marked by impaired oxidative phosphorylation, excessive oxygen species (ROS) production, and defective quality control, disrupts these processes and causes cellular and organ damage

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Tesamorelin directly stimulates the growth hormone-releasing hormone (GHRH) receptor, amplifying endogenous GHRH signaling

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Consequently, circulating testosterone declines, directly addressing the hormonal imbalance underlying PCOS-related hyperandrogenism and metabolic dysfunction in affected patients in clinical populations